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Mark P. Wentland
Professor, Department of
Chemistry and Chemical Biology
Cogswell Laboratory 332
Rensselaer Polytechnic Institute, Troy, NY
12180-3590
Recent publications:
VanAlstine, M. A.; Wentland, M. P.; Cohen, D. J.; Bidlack, J. M. "Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4'-phenyl)-phenethyl) analogues of 8-CAC." Bioorg. Med. Chem. Lett. 2007, 17, 6516-6520.
Wagman, A. S.; Wentland, M.P. "Quinolone Antibacterial Agents.” Comprehensive Medicinal Chemistry, D. Triggle and J. Taylor, Eds., Elsevier: New York, 2006, Vol. 7, pp. 567-596.
Wentland, M. P.;
VanAlstine, M.; Kucejko, R.; Lou, R; Cohen, D. J.; Parkhill, A. L.;
Bidlack, J. M. "Redefining the structure-activity relationships of
2,6-methano-3-benzazocines. Part 4.
Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido]
analogues of cyclazocine and EKC."
J. Med. Chem. 2006,
49, 5635-5639.
Wentland, M. P.; Sun, X.; Bu, Y.; Lou, R.; Cohen, D. J.; Bidlack, J. M. “Redefining the
Structure-Activity Relationships of 2,6-Methano-3-benzazocines. Part 3. 8-Thiocarboxamido and
8-Thioformamido Derivatives of Cyclazocine.” Bioorg. Med. Chem. Lett. 2005, 15, 2547-2551.
Wentland, M. P.; Lu, Q.; Lou, R.; Knapp, B.
I.; Bidlack, J. M. “Synthesis
and opioid receptor binding properties
of a highly potent 4-hydroxy analogue of naltrexone.” Bioorg. Med. Chem. Lett. 2005,
15, 2107-2110.
Wentland,
M. P.; Ye, Y.; Cioffi, C. L.; Lou, R.; Zhou, Q.; Xu, G.;
Duan, W.; Dehnhardt, C. M.; Sun, X.; Cohen, D. J.; Bidlack, J. M. “Syntheses and Opioid Receptor Binding Affinities of
8-Amino-2,6-methano-3-benzazocines.” J. Med. Chem. 2003,
46, 838-849.
Lou, R.; VanAlstine, M.; Sun, X.; Wentland, M.
P. "Preparation of
N-Hydroxysuccinimido Esters via Palladium-Catalyzed Carbonylation of Aryl
Triflates and Halides." Tetrahedron
Lett. 2003, 44, 2477-2480.
Recent
issued US Patents:
Wentland,
M. P.; "1-Alkyl4-(substituted-phenyl)piperidenes" United States Patent 7,265,226 (2007).
Wentland,
M. P.; "4-Hydroxybenzomorphans." United States Patent 7,262,298 (2007).
Wentland,
M. P.; Lou, R. "N-hydroxysuccinimide process for conversion of phenols
to carboxamides." United States Patent 7,057,035 (2005).
Wentland,
M. P. "Process for
8-carboxamido-2,6-methano-3-benzazocines." United
States Patent 6,887,998 (2005).
Wentland,
M. P. "8-Carboxamido-2,6-Methano-3-Benzazocines." United
States Patent 6,784,187 (2004).
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