Homepage for
Medicinal Chemistry (CHEM-4300/6300) - Spring, 2007
Instructor: Mark P. Wentland, Department of
Chemistry and Chemical Biology
CHEM-4300 (undergraduate) and CHEM-6300 (graduate)
will examine how organic and medicinal chemistry play a crucial role in the
discovery of agents used to treat human disease. The basis of this course is
the study of the drug discovery process from the perspective of these chemical
disciplines. Concepts to be studied are molecular targeted drug discovery, lead
compound identification and optimization, biophysical and molecular modeling
tools, biological barriers to drug action and ways chemistry can overcome them,
and the biotech industry. Topics pertinent to drug development such as
drug metabolism and clinical research will also be
discussed. Prerequisite: CHEM-2220 or CHEM-2260 or permission of instructor. 4
credit hours
Example of a lecture
module: The
Pharmacophore and drug-protein binding interactions.
For enrolled students - detailed course information will be distributed via RPI LMS