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Uncharted Territory: Scientists sequence the first carbohydrate biopolymer and researchers announce a new paradigm for drug manufacturing | |
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To uncover the entire structure of carbohydrate biopolymers, Robert Linhardt and his team borrowed a technique from the field of protein research called the proteomics top-down approach. As opposed to the bottom-up approach that first breaks apart a complex biopolymer into pieces and then rebuilds it piece by piece like a jigsaw puzzle, the top-down approach used by Linhardt and colleagues allows the researcher to picture the whole intact puzzle. In other work, Linhardt worked with researchers on a new method to build heparin. Read more. |
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