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Department of Chemistry and Chemical Biology at Rensselaer Chemistry and Chemical Biology
James A. Moore
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James A. Moore

Professor, Department of Chemistry and Chemical Biology
Rensselaer Polytechnic Institute

Education:
Ph.D., Organic-Polymer Chemistry, Polytechnic Institute of Brooklyn, 1967
B.S., Chemistry, St. John's University

Career Highlights:
Moore served as a National Institute of Health Postdoctoral Fellow at the University of Mainz in West Germany in 1967-1968. He was a Research Associate at the University of Michigan for one year before joining RPI in 1969. In 1999, he won the Presidential Green Chemistry Award for his work using paper sludge waste products in polymer research. In 2011 Prof. Moore was elected a Fellow of the American Chemical Society.

Research Areas:
Dendrimer Polyelectrolytes
Two areas of research activity impacting recent times in major areas are biotechnology and the synthesis of novel macromolecular architectures. Moore is building electrically charged macromolecules radially from a central core. The use of these novel polyelectrolytes as tools to separate proteins in an efficient and commercially viable mode is being developed in a collaborative effort with RPI’s chemical engineering department.

Novel Polymers and Polymerizations
Moore is studying ways to use materials obtainable from bio-mass (cellulose, starch, and related feed stocks) as raw materials for polymer synthesis. Currently, he is developing new classes of polymers, based on diphenolic acid (DPA), which can be efficiently produced from waste cellulose. DPA can be converted to high molecular weight hyperbranched polyester, which may be useful as blend compatibilizers. DPA can also be used to prepare functional polycarbonates similar to commercial materials but bearing a reactive carboxyl group along the polymer backbone.

Selected Publications:
“The Effect of Displacer Chemistry on Displacer Efficacy for a Suger-based Anion Exchange Displacer Library", J. Liu, S.-K. Park, J. A. Moore and S.M. Cramer, Industrial Engineering & Chemistry Research45, 9107-9114 (2006). 

"High-Affinity, Low-Molecular-Mass Displacers for Ion-Exchange Chromatography", Tugcu Nihal; Park, Sun Kyu; Moore, James A.; Cramer, Steven M., U. S. Pat.# 7,189,3240, March 13, 2007. 

"Synthesis and Characterization of Fluorescent Displacers for Online Monitoring of Displacement Chromatography", Christopher J. Morrison, Sun Kyu Park, Chester Simocko, Scott A. McCallum, Steven M. Cramer, and J. A. Moore, J. Am. Chem. Soc. 130(50), 17029-17037 (2008)

"Synthesis and Characterization of Adamantane-containing Poly(enamino-nitriles)", Dong Wan Han and J. A. Moore, Polymer, 50, 2551-2557 (2009).

"Evaluation of Chemically Selective Displacer Analogues for Protein Purification", Christopher J. Morrison, Curt M. Breneman, J.A. Moore, Steven M.Cramer, Analytical Chemistry, 81(15), 6186-6194, (2009).

“Alkyl-based Selective Displacers for Protein Purification in Ion Exchang Chromatography”, Christopher J. Morrison, J.A. Moore, Steven M. Cramer, Chromatographia, 72 (11/12), 1025-34 (2010)

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