Shekhar Garde

Professor Garde joined the department in 1999. He received his B.S. in Chemical Engineering (1992) from the University of Bombay and a Ph.D. in Chemical Engineering (1997) from the University of Delaware. He was awarded a Director's postdoctoral fellowship by the Los Alamos National Laboratory (NM) where he performed independent research during 1997-99. He uses molecular simulation and statistical mechanical tools with focus on understanding (1) three-dimensional organization of water molecules in the vicinity of nonpolar and polar solutes and protein interfaces, and (2) how this peculiar water organization induces interactions between solutes of different geometric shapes and chemical nature. These water-mediated interactions provide driving forces for proteins to fold into unique three-dimensional structures that are responsible for their various functions.