Sheldon F. Oppenheim, Ph.D.

 Department of Chemical Engineering  Office: (518) 276-2166
 Rensselaer Polytechnic Institute  
 127 Ricketts Building  E-mail - oppens@rpi.edu
 Troy, NY 12180  

 

 Research Interests  Education  Experience  Publications  Proceedings and Papers  Skills  Honors and Awards Affiliations 

 

GENERAL RESEARCH INTERESTS

Biotechnology

Bioprocessing

Bioseparations  

 

EDUCATION

8/90 to 4/96 Ph.D. In Chemical Engineering (Biochemical)

Dissertation Topic: Protein Ultrafiltration Membrane Fouling as Examined by Electron Paramagnetic Resonance Spectroscopy

The University of Iowa - Department of Chemical and Biochemical Engineering

Iowa City, IA 52242-1219

Advisor: Dr. V. G. J. Rodgers

 

9/87 to 5/90 M.E. in Chemical Engineering

Thesis Topic: A Study of Liquid - Liquid Equilibrium of an Acetone-Isooctane-Water System

Widener University - Department of Chemical Engineering

Chester, PA 19013

Advisor: Dr. David H. T. Chen

 

9/81 to 6/86 B.S. in Chemical Engineering

Drexel University - Department of Chemical Engineering

Philadelphia, PA 19104

 

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EXPERIENCE

8/98 to Present Postdoctoral Research Associate (Applied Enzymology and Separations) Course Instructor

Rensselaer Polytechnic Institute, Troy, NY 12180

Department of Chemical Engineering

Research the uses of oxidative enzymes in organic solvents.

Developing self-cleaning ultrafiltration membranes.

Chemical Engineering Thermodynamics course instructor

6/96 to present Postdoctoral Research Associate (Applied Enzymology)

The University of Iowa, Iowa City, IA 52242

Department of Chemical and Biochemical Engineering

Research the uses of oxidative enzymes in organic solvents.

Analyze effects of hepatic implants on genetic abnormalities.

Performed bacterial fermentations

 

9/91 to 5/96 Graduate Research Assistant (Protein Separation)

The University of Iowa, Iowa City, IA 52242

Department of Chemical and Biochemical Engineering

Performed detailed investigations into ultrafiltration membrane fouling.

 

5/92 to 8/92 Visiting Scientist

SmithKline Beecham, King of Prussia, PA 19406

Bioproducts Separations

Assisted in developing separation schemes for biological products.

 

9/90 to 8/91 Graduate Teaching Assistant

The University of Iowa, Iowa City, IA 52242

Department of Chemical and Biochemical Engineering

Implemented computer application in Process Control and Process Design.

 

1/90 to 7/90 Gas Chromatography Technical Consultant

Self-Employed, Philadelphia, PA 19152

Developed analytical gas chromatography methods for clients.

 

9/87 to 6/90 Graduate Assistant

Widener University, Chester, PA 19014

Department of Chemical Engineering

Implemented curriculum in the following classes: Momentum Transport, Heat Transport, Mass Transport, Mechanical Fluid Transport, Process Control, Chemical Thermodynamics, General Thermodynamics, Process Design, Process Calculations, Chemical Engineering Kinetics, Materials Engineering, and Unit Operations Laboratory.

Chemical engineering laboratory coordinator.

Installed laboratory equipment.

6/85 to 9/85 Laboratory Technician

ChemLink, Inc., (Former subsidiary of Atlantic-Richfield, Inc.,)

Newtown Square, PA 19004

IPC ChemLink - Surface Treatment Division

Developed surface treatment products. Performed laboratory tests.

Customized computer software.

 

6/84 to 12/84 Laboratory Technician

ChemLink, Inc., Newtown Square, PA 19004

Same as above.

 

6/83 to 12/83 Tutor/Programmer

Community College of Philadelphia, Philadelphia, PA 19102

Math and Science Teaching Laboratory

Tutored students in the following subjects: Calculus, Algebra,

Trigonometry, Physics, Chemistry, FORTRAN, and BASIC.

Developed educational software.

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PUBLICATIONS

Refereed Articles

1. Fabrega, A. J., A. Bosch, S. Struble, S. F. Oppenheim, S. Emery, C. Corwin, B. L. Davidson, J. Zabner, "Transplantation of Allogeneic Hepatocits Expressing h-IL10 Gene into Dalmatian Dogs: Invitro and Invivo Studies", Journal of the American Society of Transplant Surgeons, Accepted for publication March 20, 1997 (In Press).

2. Oppenheim, S. F., C. Phillips, and V. G. J. Rodgers, "Analysis of Initial Protein Surface Coverage on Fouled Ultrafiltration Membranes", Journal of Colloid and Interface Science, Volume 184, (pp. 639-651) 1996.

3. Oppenheim, S. F., J. O. Rich, G. Buettner, and V. G. J. Rodgers, "Protein Structure Changes on Adherence to Ultrafiltration Membranes. An Examination by Electron Paramagnetic Spectroscopy", Journal of Colloid and Interface Science, Volume 183, (pp. 274-279) 1996.

4. Oppenheim, S. F. , G. Buettner, and V. G. J. Rodgers, "Relationship of Rotational Correlation Time from EPR Spectroscopy and Protein -Membrane Interaction", Journal of Membrane Science, Volume 118, (pp. 133-139) September, 1996.

5. Rodgers, V. G. J., S. F. Oppenheim, and R. Datta, "Correlation of Hydraulic Permeability and Solute Uptake in Ultrafiltration Membranes of Arbitrary Pore Morphology", A.I.Ch.E. Journal, Volume 41, (pp. 1826-1829) July, 1995.

6. Oppenheim, S. F., G. Buettner, J. S. Dordick, and V. G. J. Rodgers, "Applying Electron Paramagnetic Resonance Spectroscopy to the Study of Fouling in Protein Ultrafiltration", Journal of Membrane Science, Volume 96, (pp. 289-297) November, 1994.

7. Nel, R. G., S. F. Oppenheim, and V. G. J. Rodgers, "Solution Properties Effects on Solute and Permeate Flux in Binary Protein Batch Cell Ultrafiltration", Biotechnology Progress, Volume 10 (pp. 539-542) September/October, 1994.

8. Oppenheim, S. F., and D. H. T. Chen, "Liquid - Liquid Equilibria for the Ternary System Water-Acetone-Isooctane" Journal of Chemical and Engineering Data, Volume 35, (pp. 433-436) October, 1990.

 

Proceedings, Papers, Talks, And Presentations

1. Oppenheim, S. F., and V. G. J Rodgers, "Structure Changes of Proteins Fouling Ultrafiltration Membranes as Detected by Electron Paramagentic Spectroscopy", The 1997 Fifteenth Annual Membrane Technology/Separations Planning Conference, Newton, MA, October 28, 1997.

2. Oppenheim, S. F. , and V. G. J. Rodgers, "Structure Changes of Proteins Fouling Ultrafiltration Membranes", AIChE Annual Meeting, Chicago, IL, November 14, 1996.

3. Oppenheim, S. F. , and V. G. J. Rodgers, "Examining Protein Fouling on Ultrafiltration Membranes by Electron Paramagnetic Resonance Spectroscopy", The Fine Particle Society, Chicago, IL, August, 1996.

4. Oppenheim, S. F. , and V. G. J. Rodgers, "Insights into Protein Ultrafiltration Membrane Fouling", Bioproducts Consortium, United States Department of Agriculture, Ames, IA, July 6, 1996.

5. Oppenheim, S. F. , and V. G. J. Rodgers,"Examining Shifts in Protein Structure During Ultrafiltartion by Electron Paramagnetic Resonance Spectroscopy", AIChE Annual Meeting, Miami Beach, FL, November 15, 1995.

6. Oppenheim, S. F. , and V. G. J. Rodgers,"Membrane Material: its Effect on Protein Configuration and Uptake During Ultrafiltration", AIChE Annual Meeting, San Francisco, CA November 15, 1994.

7. Oppenheim, S. F., and V. G. J. Rodgers, "Modeling Protein Uptake and Interaction in Ultrafiltration Membranes", Third Biocatalysis and Bioprocessing Conference, The University of Iowa, Iowa City, IA May 10, 1994.

8. Oppenheim, S. F. , and V. G. J. Rodgers, "An Examination of Protein-Membrane Interaction by Electron Paramagnetic Resonance Spectroscopy", AIChE Spring Meeting, Atlanta, GA, April 18, 1994.

9. Oppenheim, S. F. , and V. G. J. Rodgers, "An Examination of Transient Fouling of Ultrafiltration Membranes: A New Analytical Method", AIChE Annual Meeting, St. Louis, MO November 9, 1993.

10. Oppenheim, S. F., and V. G. J. Rodgers, "The Use of Electron Paramagnetic Resonance Spectroscopy as a Tool to Detect Ultrafiltration Membrane Fouling", Second Annual Biocatalysis and Bioprocessing Conference, The University of Iowa, Iowa City, IA October, 1992.

11. Oppenheim, S. F., J. S. Dordick, and V. G. J. Rodgers, "The Use of Electron Paramagnetic Resonance Spectroscopy as a Tool to Detect Ultrafiltration Membrane Fouling.", Bioproducts Consortium, United States Department of Agriculture, Iowa City, IA, April 1992.

12. Oppenheim, S. F., and V. G. J. Rodgers, "Reduction of Membrane Fouling in Protein Ultrafiltration", First Annual Biocatalysis and Bioprocessing Conference, The University of Iowa, Iowa City, IA, June, 1991.

Journal Referee

Biotechnology and Bioengineering

Journal of the Iowa Academy of Science

 

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LABORATORY SKILLS

 

COMPUTER SKILLS

Proficient with a variety of computers including:

· Apple Macintosh

· Prime

· Apple II series

· Cyber

· IBM PC and PC clones

· HP/Apollo

· Vax

· IBM mainframe

· SGI Indigo, Indigo2

 

Literate in the following languages:

· BASIC

· FORTRAN

Working knowledge of design and modeling programs including:

· Aspen Plus

· FLOWTRAN

· Chemcad

· Drafix CAD

· PROCESS

· TurboCAD

· Tutsim

· Tripos Sybyl

Experienced with the following operating systems:

· AP - DOS

· CP/M

· MS - DOS

· X-Windows

· Windows (3.1 & 95)

· UNIX (IRIX, HPUX)

 

Worked with the following control packages:

· Paragon

· LabTech Notebook

· LabTech Control

· LabTech Acquire

Experienced in installation of PC clone computer hardware including:

· hard drives

· modems

· printers

· computer chips (memory, processors, co-processors, UART)

· control peripherals (Opto, Analog Devices, PC Labs, National Instruments, and Metrabyte)

 

HONORS AND AWARDS

1996 Distinguished Student Leader, The University of Iowa

1995 Outstanding Graduate Student, American Institute of Chemists Foundation

1995 Nominee, Hancher-Finkbine Award

1994 Who's Who Among Students in American Universities & Colleges

1992 - 1994 National Institutes of Health Fellowship, The University of Iowa

1993 Who's Who Among Students in American Universities & Colleges

1991 Center for Biocatalysis and Bioprocessing Fellowship, The University of Iowa

1991 Who's Who Among Students in American Universities & Colleges

 

AFFILIATIONS AND OFFICES

1991 - present A.I.Ch.E. (American Institute of Chemical Engineering), Member

The University of Iowa

1997 Ethics and Research, Graduate College Orientation Seminar

1995 Ethics and Science, Undergraduate Summer Seminar for Minority Students.

1994 - 1995 Member of Graduate Seminar Organizing Committee

1994 - 1995 Ethics and Research, Graduate College Orientation Seminar

1992 - 1994 Graduate Student Senator

1992 - 1994 Graduate and Professional Student Senator

1993 Parliamentarian, Graduate Student Senate

1993 Parliamentarian, The University of Iowa Student Senate

1993 Member of The University of Iowa Graduate Council

1993 Graduate College Orientation

1993 Graduate College Dean Interview Committee

1992 Vice President for Research Interview Committee

 

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