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The Cramer Lab

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        Molecular Bioprocessing Research

 

      Smart Biopolymer Affinity Precipitation Systems

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Our group is also involved in development of an ELP based smart biopolymer fusion protein affinity precipitation systems for purification of antibodies and new classes of biopharmaceuticals. Our aim is to determine the robustness and scalability of these purification systems. We employ robotic HTS techniques to investigate the effect of a variety of operating conditions on antibody yield, purity and quality at various stages of the process. Additionally, various microscopy techniques are used to characterize the PSDs of the precipitates.

 

 

 

 

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