Publications

Publications (Referred Journal Articles)

Chung, W.K.; Hou, Y.; Freed, A; Holstein, M.; Makhatadze, G., and Cramer, S.M. “Investigation of protein binding affinity and preferred orientations in ion exchange systems using a homologous protein library”, Biotech. Bioeng. Volume 102, Issue 3 (p 869-881) (2009). (cover art featured on journal cover).

Morrison, C.J.; Godawat, R.; McCallum, S.A.; Garde, S.; Cramer, S.M. “Mechanistic Studies of Displacer-Protein Binding in Chemically Selective Displacement Systems using NMR and MD Simulations”, Biotech. Bioeng. 102(5) 1428-1437 (2009). (featured article)

Evans, S. and Cramer, S.M. "Displacer concentration effects in displacement chromatography. Implications for trace solute detection", J. Chromatogr. 1216 (1) 79-85 (2009).

Liu J, Hilton Z, Cramer S.M., “Chemically selective displacers for high-resolution protein separations in ion-exchange systems: Effect of displacer-protein interactions” Anal. Chem. 80 (9) 3357-3364 (2008)

Morrison, C.J.; Park, S.K., Simocko, C., McCallum, S.A., Cramer, S.M., Moore, J.A “Synthesis and Characterization of Fluorescent Displacers for Online Monitoring of Displacement Chromatography” J. Am. Chem. Soc 130 (50), 17029–17037 (2008).

Morrison, C.J. and Cramer, S.M. "Characterization and Design of Chemically Selective Cationic Displacers Using a Robotic High Throughput Screen," Biotech. Progress. 25 (3) 825-833 (2009).

Jindal R, Plawsky J.L., and Cramer S.M. “Synthesis and characterization of particle loaded sol-gel composite material for microfluidic chip system”, J. of Sol-Gel Sci. and Tech. 45 (2), 133-141 (2008).

Ladiwala, A., Xia, F., Luo, Q., Breneman, C.N., and Cramer, S.M., Investigation of Protein Retention and Selectivity in HIC Systems Using Quantitative Structure Retention Relationship Models, Biotech. and Bioeng., 93(5): 836-850, 2006.

Rege, K., Ladiwala, A., Hu, S., Breneman C.M., Dordick J.S., and Cramer, S.M., Investigation of DNA-Binding Properties of an Aminoglycoside-Polyamine Library Using Quantitative Structure-Activity Relationship (QSAR) Models, J.of Chem.Information and Modeling, 45(6): 1854-1863, 2005.

Ghose, S., Allen, M., Hubbard, B., Brooks, C., and Cramer, S.M., Antibody Variable Region Interactions with Protein A: Implications for the Development of Generic Purification Process, Biotech and Bioeng., 92(6):665-673, 2005.

Ladiwala, A., Rege, K., Breneman, C.M., and Cramer, S.M., A Priori Prediction of Adsorption Isotherm Parameters and Chromatographic Behavior in Ion-Exchange Systems, PNAS, 102(33): 11710-11715, 2005.

Tugcu, N., and Cramer, S.M., The Effect of Multi-Component Adsorption on Selectivity in Ion Exchange Displacement Systems, J. Chromatogr. A, 1063(1-2): 15-23, 2005.

Rege, K., Ladiwala, A., and Cramer, S.M., Multidimensional High-Throughput Screening of Displacers, Anal. Chem., 77(21): 6818-6827, 2005.

Xia, F., Nagrath, D., and Cramer, S.M., Effect of pH Changes on Water Release Values in Hydrophobic Interaction Chromatographic Systems, J. Chromatogr. A, 1079(1-2): 229-235, 2005.

Nagrath, D., Bequette, B.W., and Cramer, S.M., Messac, A., Multiobjective Optimization Strategies for Linear Gradient Chromatography, AICHE J., 51(2): 511-525, 2005.

Ghose, S., Hubbard, B., and Cramer, S.M., Protein Interactions in Hydrophobic Charge Induction Chromatography (HCIC), Biotech. Progress., 21(2): 498-508, 2005.

Jindal, R., Plawsky, J.L., and Cramer, S.M., Selective Filling for Patterning in Microfluidic Channels, Langmuir, 21(10): 4458-4463, 2005.

Jindal, R., and Cramer, S.M., On-chip Electrochromatography using Sol-Gel Immobilized Stationary Phase with UV Absorbance Detection, J. Chromatogr.. 1044: 277-285, 2004.

Rege, K., Hu, S., Moore, J., Dordick, S., and Cramer S.M., Chemoenzymatic Synthesis and High-Throughput Screening of an Aminoglycoside-Polyamine Library: Identification of High-Affinity Displacers and DNA-Binding Ligands, JACS, 126(39): 12306-12315, 2004.

Xia, F., Nagrath, D., Garde, S. and Cramer, S.M., Evaluation of Selectivity Changes in HIC Systems Using a Preferential Interaction Based Analysis, Biotech. and Bioeng., 87(3): 354-363, 2004.

Nagrath, D., Messac, A., Bequette, B.W., and Cramer, S.M., A Hybrid Model Framework for the Optimization of Preparative Chromatographic Processes, Biotech. Prog., 20(1): 162-178, 2004.

Rege, K.; Ladiwala, A.; Tugcu, N.; Breneman, C.; and Cramer, S,M., Parallel Screening of Selective and High -Affinity Displacers for Proteins in Ion-Exchange Systems, J. Chromatogr. A, 1033(1): 19-28, 2004.

Ghose, S.; Nagrath, D.; Hubbard, B; and Cramer, S.M., Use and Optimization of a Dual-Flowrate Loading Strategy to Maximize Throughput in Protein A Affinity Chromatography, Biot3ech. Prog., 20(3): 830-840, 2004.

Ladiwala, A.; Rege, K.; Breneman, C. and Cramer, S.M., Mobile Phase Salt Type Effects on Protein Retention and Selectivity in Cation Exchange Systems, Langmuir, 19(20): 8443-8454, 2003.

Tugcu, N.; Ladiwala, A.; Breneman, C. and Cramer, S.M., Identification of Chemically Selective Displacers using Parallel Batch Screening experiments and quantitative structure efficacy relationship models, Anal. Chem., 21: 5806-5816, 2003.

Tugcu, N.; Song, M.; Breneman, C. and Cramer, S.M., Prediction of the effect of mobile phase salt type on protein retention and selectivity in anion exchange systems, Anal. Chem., 75(14): 3563-3572, 2003.

Rege, K.; Tugcu, N. and Cramer, S.M., Predicting column performance in displacement chromatography from batch screening experiments, Sep. Sci. Technol., 38 (7): 1499-1517, 2003.

Sunasara, K.; Xia, F.; Gronke, R.S. and Cramer, S.M., Application of Hydrophobic Interaction Displacement Chromatography for an Industrial Protein Purification, Biotech. and Bioeng., 82 (3): 330-339, 2003.

Xia, F.; Nagrath, D. and Cramer, S.M., Modeling of adsorption in hydrophobic interaction chromatography systems using a preferential interaction quadratic isotherm, J. Chromatogr., 989 (1): 47-54, 2003.

Tugcu, N.; Deshmukh, R.R.; Sanghvi, Y.S.; et al., Displacement chromatography of anti-sense oligonucleotide and proteins using saccharin as a non-toxic displacer, React. Funct. Polym., 54 (1-3): 37-47, 2003.

Nagrath, D.; Bequette, B.W. and Cramer, S.M., Evolutionary Operation and Control of Chromatographic Processes, AIChE, 49(1): 82-95, 2003.

Tugcu, N.; Park, S.K.; Moore, J.A. and Cramer, S.M., Synthesis and characterization of high-affinity, low-molecular-mass displacers for anion-exchange chromatography, Ind. Eng. Chem. Res., 41 (25): 6482-6492, Dec 11 2002.

Song, M.H.; Breneman, C.M.; Bi, J.B.; Sukumar, N.; Bennett, K.P.; Cramer, S.M. and Tugcu, N., Prediction of protein retention times in anion-exchange chromatography systems using support vector regression, J. Chem. Inf. Comp. Sci., 42 (6): 1347-1357, Nov-Dec 2002.

Natarajan, V.; Ghose, S. and Cramer, S.M., Comparison of linear gradient and displacement separations in ion-exchange systems, Biotechnol. Bioeng., 78 (4): 365-375, May 20 2002.

Tugcu, N.; Mazza, C.; Breneman, C.; Sanghvi, Y.; Moore, J. and Cramer, S. M., High throughput screening and quantitative structure efficacy relationship models for designing displacers for anti-sense oligonucleotide purification in anion-exchange systems, Sep. Sci. Technol, 37 (7): 1667-1681, 2002.

Tugcu, N.; Bae, S.; Moore, J. A. and Cramer, S. M., The role of the stationary phase on the dynamic affinity of various low-molecular-mass displacers, J. Chromatogr., 954: pp 127-135, 2002.

Mazza, C.B.; Rege, K.; Breneman, C.; Sukumar, N.; Dordick, J.S. and Cramer, S.M., High Throughput Screening and Quantitative Structure-Efficacy Relationship Models of Potential Displacer Molecules for Ion Exchange Systems, Biotech. Bioeng., 80 (1): 60-72, Oct 5 2002.

Mazza, C.B.; Whitehead, C.E.; Breneman, C.M. and Cramer, S.M., Predictive quantitative structure retention relationship models for ion-exchange chromatography, Chromatographia, 56 (3-4): 147-152, Aug 2002.

Mazza, C. B.; Sukumar, N. and Breneman, C. M., et al. Prediction of protein retention in ion-exchange systems using molecular descriptors obtained from crystal structure, Anal. Chem., 73 (22): 5457-5461, Nov. 15, 2001

Sunasara, K. M.; Rupp, R. G. and Cramer, S. M., Purification of recombinant brain derived neurotrophic factor using reversed phase displacement chromatography, Biotechnol. Progr., 17 (5): 897-906, Sept. - Oct., 2001

Ghose, S. and Cramer, S. M., Characterization and modeling of monolithic stationary phases: application to preparative chromatography, J Chromatogr. A, 928 (1): 13-23 Aug. 31, 2001

Tugcu, N.; Deshmukh, R. R. and Sanghvi, Y. S., et al., Purification of an oligonucleotide at high column loading by high affinity, low-molecular-mass displacers, J Chromatogr. A, 923 (1-2): 65-73 July 20, 2001

Tugcu, N.; Moore, J. A. and Cramer, S. M., Synthesis and characterization of high-affinity, low molecular mass displacers for anion-exchange chromatography, submitted to Industrial and Engineering Chemistry.

Mazza, C. B.; Rege, K.; Breneman, C. M.; Dordick, J. S. and Cramer, S. M., High throughput screening and quantitative-structure efficacy relationship models of potential displacer molecules for ion exchange systems, submitted to Biotechnology and Bioengineering.

Tugcu, N.; Bae, S.; Moore, J. A. and Cramer, S. M., The role of the stationary phase on the dynamic affinity of various low-molecular-mass displacers, submitted to J. of Chromatography.

Kalra, A.; Tugcu, N.; Cramer, S. M.; and Garde, S., Salting-in and salting-out of hydrophobic solutes in aqueous salt solutions, J. Phys. Chem. B, 105 (27), 6380 -6386, 2001.

Shukla, A., Deshmukh, R., Moore, J. and Cramer, S.M.,Purification of oligonucleotides by high affinity, low molecular weight displacers, Biotechnol. Prog., 16 (6), 1064-1070 Nov.-Dec., 2000

Shukla, A., Sunasara, K. M.; Rupp, R. G. and Cramer, S. M., Hydrophobic displacement chromatography of proteins, Biotech and Bioeng, 68 (6) 672-680, 2000.

Natarajan, V.; Bequette, B.W. and Cramer, S. M., Optimization of ion exchange displacement separations. I. Validation of an iterative scheme and its use as a methods development tool, J Chromatogr. A, 876 (1-2) 51-62 April 21, 2000

Natarajan, V. and Cramer, S. M., Optimization of ion exchange displacement separations. II. Comparison of displacement separation on various ion exchange resins, J Chromatogr. A, 876 (1-2) 63-73 April 21, 2000

Natarajan, V. and Cramer, S. M., A methodology for the characterization of ion-exchange resins, Separ. Sci. Technol., 35 (11) 1719-1742, 2000.

Shukla, A. and Cramer, S. M., Bioseparations by displacement chromatography, in the Handbook of Bioseparations, Academic Press, 2000.

Mazza, C. and Cramer, S. M., Evaluation of lot-to-lot consistency in ion exchange chromatography, J Liq. Chromatogr. Relat. Techno., 22 (11) 1733-1758, 1999.

Natarajan, V. and Cramer, S. M., Modeling Shock Layers in Ion Exchange Displacement Chromatography, AIChE J. 45, 27-37, 1999.

Sane, S., Cramer, S. M. and Przybycien, T. M., A holistic approach to protein secondary structure characterization using amide I B and raman spectroscopy, Analytical Biochemistry 269, 255-272, 1999.

Sane, S., Cramer, S. M. and Przybycien, T M., Protein structure perturbations on chromatographic surfaces, Journal of Chromatography A 849,149-159, 1999.

Cramer, S. M. and Natarajan, V., Chromatography, ion exchange, in the Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis, and Bioseparation, 612-627, 1999.

Barnthouse, K. A.; Trompeter, W.; Jones, R. and Cramer, S. M., Ion-exchange displacemenmt chromatography: Scale-up and displacer clearance for recombinant human brain-derived neurotrophic factor (rHuBDNF), BioPharm 35-44, 1999.

Sunasara, K. M.; Cramer, S. M.; Hauer, C. R.; Rupp, R. G. and Shoup, V. A., Characterization of recombinant human brain-derived neurotrophic factor variants, Archives of Biochemistry and Biophysics, 372 ( 2), 248-260, 1999.

Natarajan, V. and Cramer, S. M., Modeling shock layers in ion exchange displacement chromatography, AIChE J. 45, 27-37, 1999.

Barnthouse, K. A; Trompeter, W; Jones, R.; Rupp, R. and Cramer, S. M., Ion-exchange displacement chromatography: Scale-up and displacer clearance for recombinant human brain-derived neurotrophic factor LC GC-mag, Separation Sci., 17 (11) 1028-, Nov., 1999.

Vunnum, S., Natarajan, V. and Cramer, S. M., Non-linear multicomponent gradient chromatography in IMAC systems, Sep. Sci. and Tech. 33 (16) 2465-2489, 1998.

Shukla, A. A; Bae, S. S. and Moore, J. A., et al., Synthesis and characterization of high-affinity, low molecular weight displacers for cation-exchange chromatography, Ind. Eng. Chem. Res., 37 (10) 4090-4098, 1998.

Vunnum, S.; Natarajan, V. and Cramer, S. M., IMAC: Self-sharpening of protein-modulator interfaces in frontal chromatography, J. Chromatogr. 818 (1) 31-41, 1998.

Barnthouse, K. A.; Trompeter, W.; Jones, R.; Inampudi, P.; Rupp, R. and Cramer, S. M., Purification of recombinant human brain-derived neurotropic factor (rHuBDNF) by cation-exchange displacement chromatography, J. of Biotech. 66 (2-3) 125-136, 1998.

Shukla, A. A.; Barnthouse, K. A.; Bae, S. S.; Moore, J. A. and Cramer, S. M., Structural characteristics of low molecular weight displacers for cation-exchange chromatography, J. Chromatogr. 814 (1-2), 1998.

Shukla, A. A; Bae, S. S.; Moore, J. A., and Cramer, S. M., Structural characteristics of low-molecular-mass displacers for cation-exchange chromatography - II. Role of the stationary phase, J. Chromatogr, 827 (2) 295-310, 1998.

Mazza, C.; Kundu, A.and Cramer, S. M.,Preparative ion-exchange chromatography of challenging protein separations, Biotech. Techniques, 12 ( 2) 137-141, 1998.

Goel, M.; Agrawal, V.; Kulkarni, A. K.; Cramer, S. M. and Gill, W. N., Stability and transport characteristics of reverse osmosis membranes using cyanide rinse waters, Journal of Membrane Science 141, 245-254, 1998.

Kundu, A.; Vunnum, S. and Cramer, S. M., Displacement chromatography of proteins using low molecular weight anionic displacers, Adsorption 4 (3), 1998.

Kundu, A.; Barnthouse, K. and Cramer, S. M., Selective displacement chromatography of proteins, Biotech. and Bioeng., 56 (2), 119-129, 1997.

Vunnum, S. and Cramer, S. M., IMAC: Non-linear elution chromatography of proteins, Biotech. and Bioeng., 54 (4), 373-390, 1997.

Kundu, A. Shukla, A., Barnthouse, K. Moore, J. and Cramer S. M., Displacement chromatography of proteins using sucrose octasulfate, BioPharm 10 (5), 64, 1997.

Kundu, A. and Cramer, S. M., Low molecular weight displacers for high resolution protein separations, Anal. Biochem., 248, 111-116, 1997.

Gallant, S. and Cramer, S. M., Productivity and operating regimes in protein chromatography using low molecular weight displacers, J. Chromatogr., 771, 9-22, 1997.

A. A. Shukla, R. L. Hopfer, D. N. Chakravarti, E. Bortell and S. M. Cramer, "Purification of an Antigenic Vaccine Protein by Selective Displacement Chromatography", Biotech. Prog. 14 (1998) 92-101.

Gallant, S.; Vunnum, S. and Cramer, S.M., Modeling gradient elution of proteins in ion exchange chromatography, AIChE J., 42, 2511-2520, 1996.

Brooks, C. and Cramer, S.M., Solute affinity in ion exchange displacement chromatography, Chem. Eng. Sci., 51, 3847-3860, 1996.

Vunnum, S.; Gallant, S. and Cramer, S. M., Immobilized metal displacement chromatography: displacement characteristics of traditional mobile phase modifiers, Biotechnology Progress, 12, 87-91, 1996.

Gallant, S.; Vunnum, S. and Cramer, S. M., Optimization of preparative ion-exchange chromatography of proteins-linear gradient separations, Journal of Chromatography, 725, 295-314, 1996.

Buragohain, P.; Gill, W. N. and Cramer, S. M., Novel resin based ultrapurification system for reprocessing IPA in the semiconductor industry, IEC Res., 35, 3149-3154, 1996.

Kundu, A.; Vunnum, S.; Jayaraman, G. and Cramer, S. M., Protected amino acids as novel low-molecular-weight displacers in cation-exchange displacement chromatography, Biotechnology and Bioengineering, 48, 452-460, 1995.

Kundu, A.; Vunnum, S. and Cramer, S. M., Antibiotics as low molecular weight displacers in ion exchange displacement chromatography, Journal of Chromatography, 707, 57-67, 1995.

Gallant, S.; Kundu, A. and Cramer, S. M., Optimization of step gradient separations - consideration of nonlinear adsorption, Biotechnology and Bioengineering, 47, 355-372, 1995.

Gallant, S.; Kundu, A. and Cramer, S. M., Modeling nonlinear elution of proteins in ion-exchange chromatography, Journal of Chromatography, 702, 125-142, 1995.

Vunnum, S.; Gallant, S.; Kim, Y. and Cramer, S. M., Immobilized metal affinity chromatography - modeling of nonlinear multicomponent equilibrium, Chemical Engineering Science, 50, 1785-1803, 1995.

Patrickios, C.; Gadam, S.; Hatton, T. A. and Cramer, S. M., Block methacrylic polyampholtes as protein displacers in ion-exchange chromatography, Biotechnology Progress, 11, 33-38, 1995.

Brooks, C. and Cramer, S. M., Investigation of displacer equilibrium properties and mobile phase operating conditions in ion exchange displacement chromatography, Journal of Chromatography, 693, 187-196, 1995.

Jayaraman, G.; Li, Y.; Moore, J. A. and Cramer, S. M., Ion-exchange displacement chromatography of proteins: dendritic polymers as novel displacers, Journal of Chromatography, 702,143-155, 1995.

Gadam, S.; Gallant, S. and Cramer, S. M., Transient profiles in ion-exchange displacement chromatography, AIChE Journal, 41, 1676-1686, 1995.

Gerstner, J. A.; Bell, J. and Cramer, S. M., Gibbs free energy of adsorption of biomolecules in ion-exchange systems, Biophysical Chemistry 52, 97-106, 1994.

Kim, Y. and Cramer, S. M., Experimental studies in metal affinity displacement chromatography of proteins, J. Chromatogr. 686 ( 2), 193-203, 1994.

Gadam, S. and Cramer, S. M., Salt effects in anion exchange displacement chromatography - comparison of pentosan polysulfate and dextran sulfate displacers, Chromatographia, 39, (7/8), 409-418, 1994.

Mhatre, R.; Qian, R.; Krull, I. S., Gadam, S. and Cramer, S. M., Characterization of proteins separated by displacement chromatography using low angle laser light scattering photometry Chromatographia, 38, ( 5/6), 349-354, 1994.

Cramer, S. M. and Jayaraman, G., Preparative chromatography in biotechnology, Current Opinions in Biotechnology 4, 217-225, 1993.

Wu, D.; Cramer, S. M. and Belfort, G., Enzymatic resolution of a racemic mixture using a multiphase membrane bioreactor: experiments and model verification, Biotech. Bioeng. 41, 979-990, 1993.

Gallant, S. R.; Fraleigh, S. P. and Cramer, S. M., CMAC neural network applications in chromatography, Chemometrics 18, 41-57,1993.

Jayaraman, G., Gadam, S. and Cramer, S. M., High affinity dextran based displacers for ion exchange displacement chromatography of proteins, J. Chromatogr. 630, 53-68,1993.

Gadam, S.; Jayaraman, G. and Cramer, S. M., Characterization of high affinity dextran based displacers, J. Chromatogr. 630, 37-52,1993.

Brooks, C.; Rosano, T. and Cramer, S. M., Preparative chromatographic purification of cyclosporine metabolites, Clinical Chemistry 39, 457-466, 1993.

Gerstner, J. and S. M. Cramer, Heparin as a non-toxic displacer for anion exchange displacement chromatography of proteins, BioPharm 5 (9), 42, 1992.

Brooks, C. and Cramer, S. M., Steric mass action ion exchange displacement profiles and Induced salt gradients, AIChE Journal 38 (12), 1969-1978, 1992.

Gerstner, J. and Cramer, S. M., Cation exchange displacement chromatography of proteins with protamine displacers: effect of induced salt gradients, Biotech. Progress 8, 540-545, 1992.

Gerstner, J.; Hamilton, R. and Cramer, S. M., Chromatographic membrane systems for high throughput gradient separations of biomolecules, J. Chromatogr. 596, 173-180, 1992.

Kim, Y. and Cramer, S. M., Metal chelate displacement chromatography of proteins, J. Chromatogr. 549, 89-99, 1991.

Cramer, S. M., Displacement chromatography, Nature 351, 251-252, 1991.

Freed, B. M.; Stevens, C.; Brooks, C.; Cramer, S. M.; Lampert, N. and Rosano, T. G., Assessment of the biological activity of cyclosporine metabolites using the human TURKAT cell line, Transplant Proc. 23, 980-981, 1991.

Cramer, S. M. and Subramanian, G., Recent advances in the theory and practice of displacement chromatography, Sep. Purif. Methods, 19 (1), 31-91, 1990.

Rosano, T. G.; Brooks, C. A.; Dybus, M. T.; Cramer, S. M.; Stevens, C. and Freed, B. M., Selection of an optimal assay method for monitoring cyclosporine therapy, Transplant Proc. 22 (3) 1125-1128,1990.

Wu, D.; Belfort, G. and Cramer, S. M., Enzymatic resolution with a multiphase membrane bioreactor: a theoretical analysis, I & EC Research, 29, 1612-1621, 1990.

Subramanian, G.; Phillips, M. W.; Jayaraman, G. and Cramer, S. M., Displacement chromatography of biomolecules with large particle diameter systems, J. Chromatogr., 484, 225, 1989.

Subramanian, G. and Cramer, S. M., Displacement chromatography of proteins under elevated flow rate and crossing isotherm conditions, Biotech. Progress 5 (3), 1989.

Cramer, S. M. and Horvath, Cs., Peptide synthesis and deamidation with chemically modified immobilized carboxypeptidase Y., Enzyme Microb. Technol. 11 (2), 74, 1989.

Cramer, S. M. and Horvath, Cs., Peptide synthesis with immobilized carboxypeptidase Y, Biotechnol. Bioeng. 33, 344, 1989.

Phillips, M. W., Subramanian, G. and Cramer, S. M., A theoretical optimization of operating parameters in non-ideal displacement chromatography, J. Chromatogr., 454, 1, 1988.

Subramanian, G., Phillips, M. W. and Cramer, S. M., Displacement chromatography of biomolecules, J. Chromatogr., 439, 341,1988.

Cramer, S. M. and Horvath Cs., Displacement chromatography in peptide purification, Prep. chromatogr., 1, 29, 1988.

Cramer, S. M.; Rassi, Z. and Horvath, Cs., Tandem use of carboxypeptidase Y reactor and displacement chromatograph for peptide synthesis , J. Chromatogr., 394, 305, 1987.

Cramer, S. M., Nathanael, B. and Horvath, Cs., High-performance liquid chromatography of deferoxamine and ferrioxamine: interference by iron present in the chromatographic system, J. Chromatogr., 285, 404, 1984.

Cramer, S. M.; Schornagel, J. H.; Kalghatgi, K.; Bertino, J. R. and Horvath, Cs., Occurrence and significance of D-methotrexate as a contaminant of commercial methotrexate, Cancer Res., 44, 1843, 1984.

Pitt, A. M.; Cramer, S. M.; Czernicki, A. B., Kalghatgi, K.; Horvath, Cs. and Solomon, B. A. Anisotropic membranes with carboxypeptidase G1, Appl. Biochem. Biotech., 8, 55, 1983.

Last update:01/17/04