Continuous sterilization is the rapid transfer of heat to medium through steam condensate without the use of a heat exchanger. Once the media is in a holding loop, steam is injected to the system via a nozzle. The medium stays in this loop for a predetermined holding time until the entire medium is sterile. This is more efficient than batch sterilization because instead of expending energy to heat, hold, and cool the entire system, small portions of the inlet streams are heated at a time. By looping sterile media tubes (which are at higher temperatures) past inlet tubes, the difference in temperature is used to help heat the unsterile medium. So instead of having a cold-water stream cool the sterile media, the lower temperature unsterile media stream absorbs heat from the warm stream, cooling the sterile media. Finally, the sterile media is flash cooled through an expansion valve to adjust the temperature to meet process parameters.

Advantages:
Uniform steam requirements throughout the duration of the sterilization
Simplified process control
Shorter sterilization time means less thermal degradation of medium

Disadvantages:
High demand for steam in a shorter period of time than batch
Concentration of media becomes dilute due to steam condensation
Since steam is actually dispersed in media, steam must be clean to avoid contamination
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Produced by Scott Ogoreuc and Greg DiLeo