ADDITIONAL READING

J.F. Andrews, "A mathematical model for continuous culture of microorganisms using inhibitory substrates", Biotechnol Bioengr. 10: 707-723 (1968)

Bosnjak, M., V. Topolovec, and V. Johanides, (1979) "Growth Kinetics and Antibiotic Synthesis during the Repeated Fed-batch Culture of Streptomyces", Biotechnol. Bioengr. Symp.9, 155-165

Bungay, H.R., (1971) "FERMT, A Fermentation Game Based On Process Development", Process Biochemistry 6: 38-39

C.P.L.Grady and H.C.Lim, "Biological Waste Treatment: Theory and Applications",Marcel Dekker, NY and Basel 1980

Luedeking, R., and E.L. Piret, "A kinetic study of the lactic acid fermentation. Batch process at controlled pH", J. Biochem. Microbiol. Tech. Engr. 1:393 (1959)

Mateles, R.I., (1978) "JERMFERM, A Fermentation Process Development Game", Biotechnol. Bioeng. 20: 2011-2014

Peringer, P., and H.T. Blanchere, (1979) "Modeling and Optimal Control of Bakers' Yeast Production in Repeated Fed-batch Culture", Biotechnol. Bioengr. Symp. 9, 205-213

Saguy, I., (1982) "Utilization of the 'Complex Method' to Optimize a Fermentation Process", Biotechnol. Bioengr. 24: 1519-1525

Weigand, W.A., H.C. Lim, C.C. Creagan, and R. D. Mohler, (1979) "Optimization of a Repeated Fed-batch Reactor for Maximum Cell Productivity", Biotechnol Bioengr. Symp. 9, 335-348


  • Concept of the limiting nutrient
  • Fedbatch culture
  • Relating product to growth
  • Backseeding
  • Synchronous culture
  • Teaching games
  • Back to index page for fundamentals