Fed batch fermentation
Start with a long interval and a small amount of feed to see what a typical
batch fermentation looks like. Note that the cell mass declines. We will
strive for a more constant cell concentration (green
line) by feeding more nutrient. If we are depending on cells for a bioconversion,
fed-batch is a way to overcome cell decline through death or growing too
old for the job. When you have good settings, see what happens when the
specific growth rate changes.