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BMED Course Descriptions: Printer Version
BMED-1340 Introduction to Biomedical Engineering Laboratory An introductory laboratory course for Biomedical Engineering. The student is introduced to the use of several measurement and analytical techniques. This course extends the student’s knowledge and familiarity with the discipline and provides incentive and motivation for future, more theoretical course work in BME. Taken at the first or second year. Spring term annually. 1 credit hour BMED-2200 Dynamic Systems for Biomedical Engineering Introduction of the modeling, analysis, and control of dynamic systems. Models of electrical, mechanical, electromechanical, and mass-transport systems in statevariable, input-output, and transfer function form. Linear approximations of non-linear systems. Time domain and Laplace transform solutions, Block diagrams, and feedback systems. Solutions using a standard software package with graphic user interface. Corequisites: MATH-2400, PHYS-1200. Spring term annually. 4 credit hours BMED-2940 Studies in Biomedical Engineering Each term. 1 to 4 credit hours BMED-2960 Topics in Biomedical Engineering Each term. 1 to 4 credit hours BMED-4010 Biomedical Engineering Laboratory Theory and practice of biomedical measurements. An introduction to instruments and procedures for measurement of pressure, flow, bioelectrical potentials, biomechanical and biomaterial properties, using invasive and noninvasive techniques. Transducers studied include strain gauge, differential transformer, spectrometer, blood gas electrodes, bipotential electrodes, microscope with camera, mechanical testing machine, piezoelectric transducer (or sensor), radioisotope detector. Also studied are instruments for determination of material properties. Includes in vivo use of invasive instruments. Prerequisites: BMED-2200, BMED-4500 or permission of instructor. Fall term annually. 4 credit hours BMED-4240 Tissue-Biomaterial Interactions Relationships between structure and properties of synthetic implant materials, including metals, polymers, ceramics, and composites. The emphasis is on mechanical, corrosion, and surface properties of materials. An introduction to biocompatibility with special emphasis on the interaction of biomaterials with cells and tissues. Detailed review of blood-material interactions. Case studies of implants are discussed to illustrate biomaterials selection as a key part of implant design. Prerequisites: ENGR-1600, BIOL-4290, or permission of instructor. Spring term annually. 4 credit hours BMED-4430 Bioelectric Phenomena The application of fundamental electrical engineering principles to form a basis for the solution of many different electrophysiological problems. Prerequisites: MATH-2400 and BMED-4500. Spring term annually. 4 credit hours BMED-4470 Signals and Images Principles of computer-based signal processing and imaging, covering the theoretical basis and practical applications. Topics include acquiring biomedical images, image correction and enhancement, signal and image processing, and 3-D images. Applications are to tomographic imaging, ultrasound, and microscopy. Prerequisite: BMED-2200. Spring semester, even-numbered years. 4 credit hours BMED-4490 Sensors and Instruments The engineering science that gives rise to the successful performance of medical instruments when they are connected to living systems. The physical and chemical laws that are applied to sensing, actuating, and control functions in medical devices. Models and designs are discussed in terms of optimum use of fundamental relationships, accommodating fundamental constraints, and meeting medical requirements. Consideration is given to identifying the role of instrument design in the diagnosis of diseases and the therapy to treat those diseases. Prerequisite: ECSE-2410. Spring term, odd-numbered years. 4 credit hours BMED-4500 Advanced Systems Physiology Applications of control theory and systems techniques to physiology. Emphasis is on entire systems and their interactions rather than isolated phenomena. Areas covered include cardiac, respiratory, renal, and gastrointestinal systems. Includes laboratory on the application of engineering techniques in the study of physiological systems. Prerequisite: BIOL-4290 or equivalent. Spring term annually. 4 credit hours BMED-4540 Biomechanics Application of mechanics to the study of normal, diseased, and traumatized musculo-skeletal system. Areas covered include determination of joint and muscle forces, mechanical properties of biological tissues, and structural analysis of bone-implant systems. Case studies are discussed to illustrate the role of biomechanics and biomaterials in the design of implants. Corequisite: BMED-2200. Fall term annually. 4 credit hours BMED-4600 Biomedical Engineering Design A guided approach to development of design skills. Students work individually and in teams to tackle a biomedical design problem using methods drawn as necessary from engineering and from the physical and mathematical sciences. Discussion sessions involve students in presentations of work. This is a writing-intensive course. Prerequisite: senior standing. Spring term annually. 3 credit hours BMED-4650 Introduction to Cell and Tissue Engineering This course teaches the use of engineering principles to describe cellular processes of biological, chemical, and physical nature. A quantitative approach will be used to explain the behavior of cells under various physical stimuli through the application of the laws of physics, mathematics, and physical biochemistry. The transduction of these physical stimuli into modified behavior and their impact on organ level performance/function and tissue engineering will be discussed in the case of mammalian cells. Prerequisite: A basic course in mechanics (ENGR-2530 or BMED-4540, and a basic course in transport phenomena or fluid dynamics (ENGR-2250 or equivalent), or permission of instructor. Fall semester annually. 3 credit hours BMED-6240 Tissue-Implant Interfaces An examination of biomaterial and biomechanical factors affecting events at tissue-implant interfaces, with emphasis on biomaterial surface properties plus cell and molecular interactions. Prerequisites: BIOL-4290 and BMED-4500 or permission of instructor. Fall term annually. 3 credit hours BMED-6280 Biomechanics of Soft Tissues Application of continuum mechanics in modeling the biomechanical behavior of nonmineralized tissues such as tendons, ligaments, skin, cartilage, blood vessels, etc. Topics include structure of collagen, elastin proteoglycans, and other tissue components, nonlinear elastic models (including Fung’s pseudoelasticity approach and strain energy functions), linear viscoelasticity, Fung’s quasilinear viscoelasticity, hereditary integral formulation of constitutive equations, and introduction to mixture theory. Fall term odd-numbered years. 3 credit hours BMED-6290 Biomechanics of Hard Tissues Structure-property relationships for mineralized connective tissues of the human body. Discussion centers on various types of bone (e.g., lamellar, woven) and teeth with an emphasis on models for biomechanical behavior, both in vitro and in vivo. Topics include elastic models for bone (isotropic and anisotropic), theories of yielding and fatigue, strength properties, composite and hierarchical models, and models of bone remodeling/modeling. Fall term even-numbered years. 3 credit hours BMED-6330 Cardiopulmonary Physiology Advanced, organ-level physiology of the heart, blood vessels, and lungs. Current topics in gas exchange, pulmonary ventilation, intravascular flow regulation, and transvascular exchange are explored in original articles from the current literature. Integrative aspects of physiological regulatory mechanisms are examined. Design of quantitative physiological experiments and the application of new technology are recurrent themes. Prerequisite: BMED-4500 or equivalent. Offered on demand. 3 credit hours BMED-6350 Fluid Dynamics and Transport in the Vascular Circulation The principles of convective diffusion in liquids are discussed as applied to the vascular circulation. Topics include: convective and diffusion boundary layers in internal flows with reacting and/or permeable walls, Taylor dispersion, microhydrodynamics of macromolecules and particles, Brownian motion, mass transport to arterial walls and across cell membranes. This course is intended for first year graduate students in Biomedical Engineering and undergraduate seniors with permission of the instructor. Spring term, even-numbered years. 3 credit hours BMED-6460 Advanced Biomedical Imaging Mathematical and physical analysis and computer simulations of X-ray, gamma-ray, and nuclear magnetic resonance, and optical detectors and imaging systems. Computer processing of images obtained using these systems. Prerequisite: ECSE-2410 or permission of instructor. Spring term even-numbered years. 3 credit hours BMED-6480 Adaptive Systems This course contains the fundamental theory required to design adaptive systems. Topics include parameter identification, ARMA modeling, model reference systems, model algorithmic control, selftuning systems, and adaptive filtering. Applications to physical and physiological systems are introduced. (Cross listed as ECSE-6480. Students cannot obtain credit for both this course and ECSE-6480). Prerequisite: ECSE-6400 or equivalent. Spring term odd-numbered years. 3 credit hours BMED-6500 Mechanobiology Mechanical regulation of biological systems will be discussed. Topics include principles and concepts of mechanobiology; embryogenesis and histogenesis of tissues with particular references to skeletal system; physical forces at cellular, tissue and organ level; mechanical regulation of cellular behavior, tissue growth, and organ development; limits of mechanical regulation; biochemical influences; application of mechanobiology to tissue regeneration. Prerequisites: Biomechanics (BMED-4540) or Strength of Material (ENGR-2530) with permission from the instructor. Graduate Course; offered in Spring semester (every odd year). 3 credit hours BMED-6550 Cell Biomechanics The mechanics of single cells and cells in a continuum are discussed in the context of the modulation of cell function by mechanical stresses. Topics include: mechanical forces in the natural environment of various mammalian cells (erythrocytes, leukocytes, osteoblasts, and epithelial cells), mathematical formulations of force distribution and force transmission, cell motility, models of cell membrane skeleton, cell deformability and elasticity, mechanical properties of cell membranes, and role of mechanical forces in cell structure/function. Prerequisites: Biomechanics (BMED-4540) or Strength of Materials (ENGR-2530) with permission from the instructor. Spring alternate years. 3 credit hours BMED-6960 Topics in Biomedical Engineering New courses or special course offerings are given under this number from time to time. Graduate students in biomedical engineering may pursue special interests under this number when sponsored by a biomedical engineering faculty member and with the permission of the department. Offered by individual arrangement. 1 to 4 credit hours
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