PDB file 1AV1
Structure of the truncated human apolipoprotein A-I of HDL, solved by D. W. Borhani, D. P. Rogers, J.A. Engler, & C. G. Brouillette in 1997.
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First color chain and display as cartoon to see the predominant secondary structure of this tetramer, consisting of two antiparallel dimers with overlapping ends.
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Note the positions of prolines. What is their role?
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Type in select *a,
*b and display as spacefill.
Select protein-hydrophobic and specify a
color. Select protein-polar and specify a
Select protein-backbone and then select hide.
Why is this protein referred to as amphipathic?
What interactions hold the dimer together?
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