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The Information Systems Engineering (ISE) concentration prepares students to succeed in the Information Systems (IS) profession as a technically competent systems analyst, software designer, and application developer. The IS profession is generally made up of business analysts, systems designers, and programmers; where business analysts identify requirements with end users, systems designers construct the information architecture (networks, databases, and applications) required, and programmers develop the software implementation.

Graduates of this ISE concentration will claim the middle domain, systems designer, while being perfectly capable of moving into either of the other two domains. The graduates could go anywhere information systems are used, meaning essentially any modern organizations in any sector of the economy. The ISE curriculum combines competencies in databases and software engineering with technical analysis and design tools to give graduates a unique blending of knowledge .