CHEM-6300

Medicinal Chemistry

The organic chemistry of drug discovery and synthesis will be the focus of this course. Starting with the basic concepts of molecular-targeted drug discovery, the process of lead identification will be explored with special emphasis on drug screening and combinatorial chemistry. The roles of computational chemistry, molecular modeling, and biophysical methods in the understanding of the relationship between structure and biological activity will be studied. The chirality of drugs from both the biological and synthetic perspectives will also be explored. Prerequisite: CHEM-6210 or permission of instructor.

3 credit hours