BCBP-4870

Crystallographic Analysis of Protein Structure

X-ray crystallography is the method of choice for determining the three-dimensional structure of biological macromolecules. We will cover the crystallographic method, its theory and practice, followed by a detailed exploration of selected protein structures. Other topics include the thermodynamics of structure formation, structure prediction form primary sequence, and molecular dynamics. (Students cannot obtain credit for both this course and BCBP-6870.) Prerequisite: BCBP-4760, MATH-1020, and PHYS-1200 or equivalents. Fall term odd numbered years.

4 credit hours